ALPHLARD: a Bayesian method for analyzing HLA genes from whole genome sequence data

BACKGROUND: Although human leukocyte antigen (HLA) genotyping based on amplicon, whole exome sequence (WES), and RNA sequence data has been achieved in recent years, accurate genotyping from whole genome sequence (WGS) data remains a challenge due to the low depth. Furthermore, there is no method to...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Hayashi, Shuto, Yamaguchi, Rui, Mizuno, Shinichi, Komura, Mitsuhiro, Miyano, Satoru, Nakagawa, Hidewaki, Imoto, Seiya
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211482/
https://ncbi.nlm.nih.gov/pubmed/30384854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5169-9
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