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Structure-Activity Relationships of Bisphosphate Nucleotide Derivatives as P2Y(1) Receptor Antagonists and Partial Agonists
The P2Y(1) receptor is present in the heart, in skeletal and various smooth muscles, and in platelets, where its activation is linked to aggregation. Adenosine 3′,5′- and 2′,5′-bisphosphates have been identified as selective antagonists at the P2Y(1) receptor (Boyer et al. Mol. Pharmacol. 1996, 50,...
Shranjeno v:
| izdano v: | J Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6211166/ https://ncbi.nlm.nih.gov/pubmed/10229631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm980657j |
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