A Natural Variant of the Signaling Molecule Vav1 Enhances Susceptibility to Myasthenia Gravis and Influences the T Cell Receptor Repertoire

The guanine nucleotide exchange factor Vav1 is essential for transducing T cell receptor (TCR) signals and plays an important role in T cell development and activation. Previous genetic studies identified a natural variant of Vav1 characterized by the substitution of an arginine (R) residue by a try...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bernard, Isabelle, Sacquin, Antoine, Kassem, Sahar, Benamar, Mehdi, Colacios, Céline, Gador, Mylène, Pérals, Corine, Fazilleau, Nicolas, Saoudi, Abdelhadi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210741/
https://ncbi.nlm.nih.gov/pubmed/30410484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02399
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados