VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis

OBJECTIVE: To identify novel genetic loci that predispose to early-onset myasthenia gravis (EOMG) applying a two-stage association study, exploration, and replication strategy. METHODS: Thirty-four loci and one confirmation loci, human leukocyte antigen (HLA)-DRA, were selected as candidate genes by...

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Detalhes bibliográficos
Main Authors: Avidan, Nili, Le Panse, Rozen, Harbo, Hanne F, Bernasconi, Pia, Poulas, Konstantinos, Ginzburg, Elizabeta, Cavalcante, Paola, Colleoni, Lara, Baggi, Fulvio, Antozzi, Carlo, Truffault, Frédérique, Horn-Saban, Shirley, Pöschel, Simone, Zagoriti, Zoi, Maniaol, Angelina, Lie, Benedicte A, Bernard, Isabelle, Saoudi, Abdelhadi, Illes, Zsolt, Casasnovas Pons, Carlos, Melms, Arthur, Tzartos, Socrates, Willcox, Nicholas, Kostera-Pruszczyk, Anna, Tallaksen, Chantal, Mantegazza, Renato, Berrih-Aknin, Sonia, Miller, Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184684/
https://ncbi.nlm.nih.gov/pubmed/25356403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51
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