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Integrative analysis of methylome and transcriptome in human blood identifies extensive sex- and immune cell-specific differentially methylated regions

The relationship between DNA methylation and gene expression is complex and elusive. To further elucidate these relations, we performed an integrative analysis of the methylome and transcriptome of 4 circulating immune cell subsets (B cells, monocytes, CD4(+), and CD8(+) T cells) from healthy female...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Mamrut, Shimrat, Avidan, Nili, Staun-Ram, Elsebeth, Ginzburg, Elizabeta, Truffault, Frederique, Berrih-Aknin, Sonia, Miller, Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844205/
https://ncbi.nlm.nih.gov/pubmed/26291385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1084462
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