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Integrative analysis of methylome and transcriptome in human blood identifies extensive sex- and immune cell-specific differentially methylated regions

The relationship between DNA methylation and gene expression is complex and elusive. To further elucidate these relations, we performed an integrative analysis of the methylome and transcriptome of 4 circulating immune cell subsets (B cells, monocytes, CD4(+), and CD8(+) T cells) from healthy female...

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Bibliographische Detailangaben
Veröffentlicht in:Epigenetics
Hauptverfasser: Mamrut, Shimrat, Avidan, Nili, Staun-Ram, Elsebeth, Ginzburg, Elizabeta, Truffault, Frederique, Berrih-Aknin, Sonia, Miller, Ariel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4844205/
https://ncbi.nlm.nih.gov/pubmed/26291385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1084462
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