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Functional defect of regulatory CD4(+)CD25(+) T cells in the thymus of patients with autoimmune myasthenia gravis

Thymus-derived CD4(+)CD25(+) regulatory T (Treg) cells are essential for the maintenance of immunologic self-tolerance. Despite their critical role in the active suppression of experimental autoimmune disorders, little is known about their involvement in human autoimmune diseases. Myasthenia gravis...

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Detalhes bibliográficos
Main Authors: Balandina, Anna, Lécart, Sandrine, Dartevelle, Philippe, Saoudi, Abdelhadi, Berrih-Aknin, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847365/
https://ncbi.nlm.nih.gov/pubmed/15454488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-11-3900
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