A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

The guanine nucleotide exchange factor Vav1 is essential for transducing T cell antigen receptor signals and therefore plays an important role in T cell development and activation. Our previous genetic studies identified a locus on rat chromosome 9 that controls the susceptibility to neuroinflammati...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Kassem, Sahar, Gaud, Guillaume, Bernard, Isabelle, Benamar, Mehdi, Dejean, Anne S., Liblau, Roland, Fournié, Gilbert J., Colacios, Céline, Malissen, Bernard, Saoudi, Abdelhadi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954684/
https://ncbi.nlm.nih.gov/pubmed/27438086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006185
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados