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Rho-GTPases as key regulators of T lymphocyte biology

Rho-GTPases belong to the Ras superfamily and are crucial signal transducing proteins downstream of many receptors. In general, the Rho-GTPases function as molecular switches, cycling between inactive (GDP-bound) and active (GTP-bound) states. The activated GTP bound Rho-GTPases interact with a broa...

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Detalhes bibliográficos
Main Authors: Saoudi, Abdelhadi, Kassem, Sahar, Dejean, Anne, Gaud, Guillaume
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160340/
https://ncbi.nlm.nih.gov/pubmed/24825161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.28208
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