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Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists
A screen conducted with nearly 100,000 compounds and a surrogate functional assay for stimulation of an immune response that measured the release of TNF-α from treated human THP-1 myeloid cells differentiated along the macrophage line led to the discovery of the diprovocims. Unique to these efforts...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6209530/ https://ncbi.nlm.nih.gov/pubmed/30272974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b09223 |
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