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Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau
In Alzheimer’s disease (AD) and other tauopathies, the cytosolic protein Tau misfolds and forms intracellular aggregates which accumulate within the brain leading to neurodegeneration. Clinical progression is tightly linked to the progressive spread of Tau pathology throughout the brain, and several...
Gorde:
| Argitaratua izan da: | Acta Neuropathol |
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| Egile Nagusiak: | , , , , , , , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer Berlin Heidelberg
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6208734/ https://ncbi.nlm.nih.gov/pubmed/30238240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1911-2 |
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