Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau

In Alzheimer’s disease (AD) and other tauopathies, the cytosolic protein Tau misfolds and forms intracellular aggregates which accumulate within the brain leading to neurodegeneration. Clinical progression is tightly linked to the progressive spread of Tau pathology throughout the brain, and several...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Acta Neuropathol
Autors principals: Courade, Jean-Philippe, Angers, Rachel, Mairet-Coello, Georges, Pacico, Nathalie, Tyson, Kerry, Lightwood, Daniel, Munro, Rebecca, McMillan, David, Griffin, Robert, Baker, Terry, Starkie, Dale, Nan, Ruodan, Westwood, Marta, Mushikiwabo, Marie-Laetitia, Jung, Sophie, Odede, Geofrey, Sweeney, Berni, Popplewell, Andrew, Burgess, Gillian, Downey, Patrick, Citron, Martin
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2018
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208734/
https://ncbi.nlm.nih.gov/pubmed/30238240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1911-2
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars