CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeostasis of human vascular cells

Vascular cell functionality is critical to blood vessel homeostasis. Constitutive NF-κB activation in vascular cells results in chronic vascular inflammation, leading to various cardiovascular diseases. However, how NF-κB regulates human blood vessel homeostasis remains largely elusive. Here, using...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Wang, Ping, Liu, Zunpeng, Zhang, Xiaoqian, Li, Jingyi, Sun, Liang, Ju, Zhenyu, Li, Jian, Chan, Piu, Liu, Guang-Hui, Zhang, Weiqi, Song, Moshi, Qu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208479/
https://ncbi.nlm.nih.gov/pubmed/29968158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-018-0560-5
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