CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation

An efficient genome editing approach had been established to construct the stable transgenic cell lines in the domestic chicken (Gallus gallus domesticus) at present. Our objectives were to investigate gene function in the differentiation process of chicken embryonic stem cells (ESCs) into spermatog...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Zhang, Yani, Wang, Yingjie, Zuo, Qisheng, Li, Dong, Zhang, Wenhui, Wang, Fei, Ji, Yanqin, Jin, Jing, Lu, Zhenyu, Wang, Man, Zhang, Chen, Li, Bichun
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325261/
https://ncbi.nlm.nih.gov/pubmed/28234938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172207
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