CRISPR/Cas9 mediated chicken Stra8 gene knockout and inhibition of male germ cell differentiation

An efficient genome editing approach had been established to construct the stable transgenic cell lines in the domestic chicken (Gallus gallus domesticus) at present. Our objectives were to investigate gene function in the differentiation process of chicken embryonic stem cells (ESCs) into spermatog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhang, Yani, Wang, Yingjie, Zuo, Qisheng, Li, Dong, Zhang, Wenhui, Wang, Fei, Ji, Yanqin, Jin, Jing, Lu, Zhenyu, Wang, Man, Zhang, Chen, Li, Bichun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325261/
https://ncbi.nlm.nih.gov/pubmed/28234938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172207
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