Structural and Biochemical Characterization of Endoribonuclease Nsp15 Encoded by Middle East Respiratory Syndrome Coronavirus

Nonstructural protein 15 (Nsp15) encoded by coronavirus (CoV) is a nidoviral uridylate-specific endoribonuclease (NendoU) that plays an essential role in the life cycle of the virus. Structural information on this crucial protein from the Middle East respiratory syndrome CoV (MERS-CoV), which is let...

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Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Zhang, Lianqi, Li, Lei, Yan, Liming, Ming, Zhenhua, Jia, Zhihui, Lou, Zhiyong, Rao, Zihe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6206473/
https://ncbi.nlm.nih.gov/pubmed/30135128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00893-18
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