Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis

To date, an effective therapeutic treatment that confers strong attenuation toward coronaviruses (CoVs) remains elusive. Of all the potential drug targets, the helicase of CoVs is considered to be one of the most important. Here, we first present the structure of the full-length Nsp13 helicase of SA...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Jia, Zhihui, Yan, Liming, Ren, Zhilin, Wu, Lijie, Wang, Jin, Guo, Jing, Zheng, Litao, Ming, Zhenhua, Zhang, Lianqi, Lou, Zhiyong, Rao, Zihe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Structural Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614802/
https://ncbi.nlm.nih.gov/pubmed/31131400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz409
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