Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis

To date, an effective therapeutic treatment that confers strong attenuation toward coronaviruses (CoVs) remains elusive. Of all the potential drug targets, the helicase of CoVs is considered to be one of the most important. Here, we first present the structure of the full-length Nsp13 helicase of SA...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Jia, Zhihui, Yan, Liming, Ren, Zhilin, Wu, Lijie, Wang, Jin, Guo, Jing, Zheng, Litao, Ming, Zhenhua, Zhang, Lianqi, Lou, Zhiyong, Rao, Zihe
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614802/
https://ncbi.nlm.nih.gov/pubmed/31131400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz409
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