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The Coronavirus Endoribonuclease Nsp15 Interacts with Retinoblastoma Tumor Suppressor Protein

Coronaviruses encode an endoribonuclease, Nsp15, which has a poorly defined role in infection. Sequence analysis revealed a retinoblastoma protein-binding motif (LXCXE/D) in the majority of the Nsp15 of the severe acute respiratory syndrome coronavirus (SARS-CoV) and its orthologs in the alpha and b...

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Autori principali: Bhardwaj, Kanchan, Liu, Pinghua, Leibowitz, Julian L., Kao, C. Cheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318636/
https://ncbi.nlm.nih.gov/pubmed/22301153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07012-11
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