Biochemical and Genetic Analyses of Murine Hepatitis Virus Nsp15 Endoribonuclease

The goal of this project was to better define the relationship between the endoribonuclease activity of murine hepatitis virus (MHV) Nsp15 (mNsp15) and its role in virus infection. Molecular modeling demonstrated that the catalytic residues of mNsp15 are superimposable with its severe acute respirat...

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Detalhes bibliográficos
Main Authors: Kang, Hyojeung, Bhardwaj, Kanchan, Li, Yi, Palaninathan, Satheesh, Sacchettini, James, Guarino, Linda, Leibowitz, Julian L., Kao, C. Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168834/
https://ncbi.nlm.nih.gov/pubmed/17898055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00547-07
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