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Biochemical and Genetic Analyses of Murine Hepatitis Virus Nsp15 Endoribonuclease

The goal of this project was to better define the relationship between the endoribonuclease activity of murine hepatitis virus (MHV) Nsp15 (mNsp15) and its role in virus infection. Molecular modeling demonstrated that the catalytic residues of mNsp15 are superimposable with its severe acute respirat...

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Main Authors: Kang, Hyojeung, Bhardwaj, Kanchan, Li, Yi, Palaninathan, Satheesh, Sacchettini, James, Guarino, Linda, Leibowitz, Julian L., Kao, C. Cheng
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168834/
https://ncbi.nlm.nih.gov/pubmed/17898055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00547-07
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