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Mutational Analysis of the SARS Virus Nsp15 Endoribonuclease: Identification of Residues Affecting Hexamer Formation
The severe acute respiratory syndrome (SARS) coronavirus virus non-structural protein 15 is a Mn(2+)-dependent endoribonuclease with specificity for cleavage at uridylate residues. To better understand structural and functional characteristics of Nsp15, 22 mutant versions of Nsp15 were produced in E...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Ltd.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7094243/ https://ncbi.nlm.nih.gov/pubmed/16216269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2005.09.007 |
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