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CRISPR/Cas9-mediated gene targeting during embryogenesis in swine

Ability to disrupt genes is essential in elucidating gene function. Unlike rodents or amphibians, it has been difficult to generate gene targeted embryos in large animals. Therefore, studies of early embryo development have been hampered due to the limitation. A recent technology suggests that targe...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Ryu, Junghyun, Lee, Kiho
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205924/
https://ncbi.nlm.nih.gov/pubmed/28456969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6988-3_16
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