Frequency of off-targeting in genome edited pigs produced via direct injection of the CRISPR/Cas9 system into developing embryos

BACKGROUND: The CRISPR/Cas9 system can effectively introduce site-specific modifications to the genome. The efficiency is high enough to induce targeted genome modifications during embryogenesis, thus increasing the efficiency of producing genetically modified animal models and having potential clin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Biotechnol
Main Authors: Carey, Kayla, Ryu, Junghyun, Uh, Kyungjun, Lengi, Andrea J., Clark-Deener, Sherrie, Corl, Benjamin A., Lee, Kiho
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501304/
https://ncbi.nlm.nih.gov/pubmed/31060546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0517-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados