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Frequency of off-targeting in genome edited pigs produced via direct injection of the CRISPR/Cas9 system into developing embryos

BACKGROUND: The CRISPR/Cas9 system can effectively introduce site-specific modifications to the genome. The efficiency is high enough to induce targeted genome modifications during embryogenesis, thus increasing the efficiency of producing genetically modified animal models and having potential clin...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:BMC Biotechnol
मुख्य लेखकों: Carey, Kayla, Ryu, Junghyun, Uh, Kyungjun, Lengi, Andrea J., Clark-Deener, Sherrie, Corl, Benjamin A., Lee, Kiho
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501304/
https://ncbi.nlm.nih.gov/pubmed/31060546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-019-0517-7
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