Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted

While T cells are important for the pathogenesis of systemic lupus erythematosus (SLE) and lupus nephritis, little is known about how T cells function after infiltrating the kidney. The current paradigm suggests that kidney-infiltrating T cells (KITs) are activated effector cells contributing to tis...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Tilstra, Jeremy S., Avery, Lyndsay, Menk, Ashley V., Gordon, Rachael A., Smita, Shuchi, Kane, Lawrence P., Chikina, Maria, Delgoffe, Greg M., Shlomchik, Mark J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205402/
https://ncbi.nlm.nih.gov/pubmed/30130253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120859
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