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Lupus and proliferative nephritis are PAD4 independent in murine models

Though recent reports suggest that neutrophil extracellular traps (NETs) are a source of antigenic nucleic acids in systemic lupus erythematosus (SLE), we recently showed that inhibition of NETs by targeting the NADPH oxidase complex via cytochrome b-245, β polypeptide (cybb) deletion exacerbated di...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Gordon, Rachael A., Herter, Jan M., Rosetti, Florencia, Campbell, Allison M., Nishi, Hiroshi, Kashgarian, Michael, Bastacky, Sheldon I., Marinov, Anthony, Nickerson, Kevin M., Mayadas, Tanya N., Shlomchik, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436537/
https://ncbi.nlm.nih.gov/pubmed/28515361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92926
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