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Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne

A new anthraquinone-fused enediyne, yangpumicin A (YPM A, 1), along with four Bergman cyclization congeners (YPM B–E, 2–5), was isolated from Micromonospora yangpuensis DSM 45577 after mining enediyne biosynthetic gene clusters from public actinobacterial genome databases and prioritizing the hits b...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Yan, Xiaohui, Chen, Jian-Jun, Adhikari, Ajeeth, Yang, Dong, Crnovcic, Ivana, Wang, Nan, Chang, Chin-Yuan, Rader, Christoph, Shen, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204215/
https://ncbi.nlm.nih.gov/pubmed/29086572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03120
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