טוען...
Challenges and opportunities to develop enediyne natural products as payloads for antibody-drug conjugates
Calicheamicin, the payload of the antibody-drug-conjugates (ADCs) gemtuzumab ozogamicin (Mylotarg®) and inotuzumab ozogamicin (Besponsa®), belongs to the class of enediyne natural products. Since the isolation and structural determination of the neocarzinostatin chromophore in 1985, the enediynes ha...
שמור ב:
| הוצא לאור ב: | Antib Ther |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7850032/ https://ncbi.nlm.nih.gov/pubmed/33554043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbab001 |
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