FoxO transcription factors influence cartilage maturation, homeostasis and osteoarthritis pathogenesis by modulating autophagy and proteoglycan 4

Aging is a main risk factor for osteoarthritis (OA). FoxO transcription factors protect against cellular and organismal aging and FoxO expression in cartilage is reduced with aging and in OA. To investigate FoxO in cartilage function, single and triple FoxO1/3/4 floxed mice were crossed with Col2-Cr...

全面介紹

Na minha lista:
書目詳細資料
發表在:Sci Transl Med
Main Authors: Matsuzaki, Tokio, Alvarez-Garcia, Oscar, Mokuda, Sho, Nagira, Keita, Olmer, Merissa, Gamini, Ramya, Miyata, Kohei, Akasaki, Yukio, Su, Andrew I., Asahara, Hiroshi, Lotz, Martin K.
格式: Artigo
語言:Inglês
出版: 2018
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204214/
https://ncbi.nlm.nih.gov/pubmed/29444976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aan0746
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍