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Excessive plasmin compromises hepatic sinusoidal vascular integrity after acetaminophen overdose
The serine protease plasmin degrades extracellular matrix (ECM) components both directly and indirectly through activation of matrix metalloproteinases. Excessive plasmin activity and subsequent ECM degradation causes hepatic sinusoidal fragility and hemorrhage in developing embryos. We report here...
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| Publicado no: | Hepatology |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204085/ https://ncbi.nlm.nih.gov/pubmed/29729197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30070 |
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