The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture

Physiological hypoxia can trigger transcriptional events that influence many developmental processes during mammalian embryogenesis. One way that hypoxia affects transcription is by engaging chromatin-remodeling complexes. We now report that chromodomain helicase DNA binding protein 4 (CHD4), an enz...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Colijn, Sarah, Gao, Siqi, Ingram, Kyle G., Menendez, Matthew, Muthukumar, Vijay, Silasi-Mansat, Robert, Chmielewska, Joanna J., Hinsdale, Myron, Lupu, Florea, Griffin, Courtney T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206092/
https://ncbi.nlm.nih.gov/pubmed/31235857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0376-8
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