The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture

Physiological hypoxia can trigger transcriptional events that influence many developmental processes during mammalian embryogenesis. One way that hypoxia affects transcription is by engaging chromatin-remodeling complexes. We now report that chromodomain helicase DNA binding protein 4 (CHD4), an enz...

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Publicado no:Cell Death Differ
Main Authors: Colijn, Sarah, Gao, Siqi, Ingram, Kyle G., Menendez, Matthew, Muthukumar, Vijay, Silasi-Mansat, Robert, Chmielewska, Joanna J., Hinsdale, Myron, Lupu, Florea, Griffin, Courtney T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206092/
https://ncbi.nlm.nih.gov/pubmed/31235857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0376-8
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