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In vivo–generated thrombin and plasmin do not activate the complement system in baboons

Sepsis concurrently activates both coagulation and complement systems. Although complement activation by bacteria is well documented, work in mice and in vitro suggests that coagulation proteases can directly cleave complement proteins. We aimed to determine whether generation of coagulation proteas...

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Publicat a:Blood
Autors principals: Keshari, Ravi S., Silasi, Robert, Lupu, Cristina, Taylor, Fletcher B., Lupu, Florea
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731087/
https://ncbi.nlm.nih.gov/pubmed/29021229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-788216
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