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In vivo–generated thrombin and plasmin do not activate the complement system in baboons

Sepsis concurrently activates both coagulation and complement systems. Although complement activation by bacteria is well documented, work in mice and in vitro suggests that coagulation proteases can directly cleave complement proteins. We aimed to determine whether generation of coagulation proteas...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Keshari, Ravi S., Silasi, Robert, Lupu, Cristina, Taylor, Fletcher B., Lupu, Florea
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731087/
https://ncbi.nlm.nih.gov/pubmed/29021229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-788216
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