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Excessive plasmin compromises hepatic sinusoidal vascular integrity after acetaminophen overdose
The serine protease plasmin degrades extracellular matrix (ECM) components both directly and indirectly through activation of matrix metalloproteinases. Excessive plasmin activity and subsequent ECM degradation causes hepatic sinusoidal fragility and hemorrhage in developing embryos. We report here...
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| 出版年: | Hepatology |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6204085/ https://ncbi.nlm.nih.gov/pubmed/29729197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30070 |
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