Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling

The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH) in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated that high-fat-non-cholesterol-fed mice developed simple steatosis, whilst high-fat-high-cholesterol-fed mice developed NA...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Liang, Jessie Qiaoyi, Teoh, Narcissus, Xu, Lixia, Pok, Sharon, Li, Xiangchun, Chu, Eagle S. H., Chiu, Jonathan, Dong, Ling, Arfianti, Evi, Haigh, W. Geoffrey, Yeh, Matthew M., Ioannou, George N., Sung, Joseph J. Y., Farrell, Geoffrey, Yu, Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203711/
https://ncbi.nlm.nih.gov/pubmed/30367044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06931-6
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