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Cholesterol Crystals in Hepatocyte Lipid Droplets Are Strongly Associated With Human Nonalcoholic Steatohepatitis

It is unclear what drives the development of fibrosing nonalcoholic steatohepatitis (NASH). We aimed to determine whether cholesterol crystallization within hepatocyte lipid droplets (LDs) distinguishes patients with fibrosing NASH from patients with isolated hepatic steatosis and to study pathways...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Ioannou, George N., Landis, Charles S., Jin, Ga‐Young, Haigh, W. Geoffrey, Farrell, Geoffrey C., Kuver, Rahul, Lee, Sum P., Savard, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545865/
https://ncbi.nlm.nih.gov/pubmed/31168512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1348
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