Dietary cholesterol promotes steatohepatitis related hepatocellular carcinoma through dysregulated metabolism and calcium signaling

The underlining mechanisms of dietary cholesterol and nonalcoholic steatohepatitis (NASH) in contributing to hepatocellular carcinoma (HCC) remain undefined. Here we demonstrated that high-fat-non-cholesterol-fed mice developed simple steatosis, whilst high-fat-high-cholesterol-fed mice developed NA...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liang, Jessie Qiaoyi, Teoh, Narcissus, Xu, Lixia, Pok, Sharon, Li, Xiangchun, Chu, Eagle S. H., Chiu, Jonathan, Dong, Ling, Arfianti, Evi, Haigh, W. Geoffrey, Yeh, Matthew M., Ioannou, George N., Sung, Joseph J. Y., Farrell, Geoffrey, Yu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203711/
https://ncbi.nlm.nih.gov/pubmed/30367044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06931-6
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