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Homo- and Heterodimerization of Proteins in Cell Signaling: Inhibition and Drug Design

Protein dimerization controls many physiological processes in the body. Proteins form homo-, hetero-, or oligomerization in the cellular environment to regulate the cellular processes. Any deregulation of these processes may result in a disease state. Protein–protein interactions (PPIs) can be inhib...

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Détails bibliographiques
Publié dans:Adv Protein Chem Struct Biol
Auteurs principaux: Singh, Sitanshu S., Jois, Seetharama D.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203451/
https://ncbi.nlm.nih.gov/pubmed/29459028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.apcsb.2017.08.003
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