Cargando...
ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance
Certain commensal Escherichia coli contain the clb biosynthetic gene cluster that codes for small molecule prodrugs known as precolibactins. Precolibactins are converted to colibactins by N-deacylation; the latter are postulated to be genotoxic and to contribute to colorectal cancer formation. Thoug...
Gardado en:
| Publicado en: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6202678/ https://ncbi.nlm.nih.gov/pubmed/29112397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09971 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|