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Frontal Affinity Chromatography—Mass Spectrometry Useful for Characterization of New Ligands for GPR17 Receptor
The application of frontal affinity chromatography−mass spectrometry (FAC−MS), along with molecular modeling studies, to the screening of potential drug candidates toward the recently deorphanized G-protein-coupled receptor (GPCR) GPR17 is shown. GPR17 is dually activated by uracil nucleotides and c...
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| Publicado no: | J Med Chem |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201305/ https://ncbi.nlm.nih.gov/pubmed/20394377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901691y |
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