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2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors

The synthesis of a series of 9-ethyladenine derivatives bearing alkynyl chains in 2- or 8-position was undertaken, based on the observation that replacement of the sugar moiety in adenosine derivatives with alkyl groups led to adenosine receptor antagonists. All the synthesized compounds were tested...

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Bibliografski detalji
Glavni autori: Volpini, Rosaria, Costanzi, Stefano, Lambertucci, Catia, Vittori, Sauro, Martini, Claudia, Trincavelli, M. Letizia, Klotz, Karl-Norbert, Cristalli, Gloria
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096531/
https://ncbi.nlm.nih.gov/pubmed/18404502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-005-6216-y
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