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Molecular modelling study of 2-phenylethynyladenosine (PEAdo) derivatives as highly selective A(3) adenosine receptor ligands
A series of 2-phenylethynyladenosine (PEAdo) derivatives substituted in the N(6)- and 4′position was synthesised and the new derivatives were tested at the four human adenosine receptors stably transfected into Chinese hamster ovary (CHO) cells, using radioligand binding studies (A(1), A(2A), A(3))...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Netherlands
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096654/ https://ncbi.nlm.nih.gov/pubmed/18404461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-006-9010-6 |
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