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Molecular modelling study of 2-phenylethynyladenosine (PEAdo) derivatives as highly selective A(3) adenosine receptor ligands

A series of 2-phenylethynyladenosine (PEAdo) derivatives substituted in the N(6)- and 4′position was synthesised and the new derivatives were tested at the four human adenosine receptors stably transfected into Chinese hamster ovary (CHO) cells, using radioligand binding studies (A(1), A(2A), A(3))...

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Main Authors: Dal Ben, Diego, Lambertucci, Catia, Taffi, Sara, Vittori, Sauro, Volpini, Rosaria, Cristalli, Gloria, Klotz, Karl-Norbert
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer Netherlands 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096654/
https://ncbi.nlm.nih.gov/pubmed/18404461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-006-9010-6
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