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New 2,6,9-trisubstituted adenines as adenosine receptor antagonists: a preliminary SAR profile

A new series of 2,6,9-trisubstituted adenines (5–14) have been prepared and evaluated in radioligand binding studies for their affinity at the human A(1), A(2A) and A(3) adenosine receptors and in adenylyl cyclase experiments for their potency at the human A(2B) subtype. From this preliminary study...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lambertucci, Catia, Cristalli, Gloria, Dal Ben, Diego, Kachare, Dhuldeo D., Bolcato, Chiara, Klotz, Karl-Norbert, Spalluto, Giampiero, Volpini, Rosaria
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Netherlands 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072915/
https://ncbi.nlm.nih.gov/pubmed/18404447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-007-9068-9
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