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New 2,6,9-trisubstituted adenines as adenosine receptor antagonists: a preliminary SAR profile
A new series of 2,6,9-trisubstituted adenines (5–14) have been prepared and evaluated in radioligand binding studies for their affinity at the human A(1), A(2A) and A(3) adenosine receptors and in adenylyl cyclase experiments for their potency at the human A(2B) subtype. From this preliminary study...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2072915/ https://ncbi.nlm.nih.gov/pubmed/18404447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-007-9068-9 |
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