Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach

Lignende værker

• GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors
  af: Parravicini, Chiara, et al.
  Udgivet: (2008)
• Frontal Affinity Chromatography—Mass Spectrometry Useful for Characterization of New Ligands for GPR17 Receptor
  af: Calieri, Enrica, et al.
  Udgivet: (2010)
• Computational Study of Protein-Ligand Unbinding for Enzyme Engineering
  af: Marques, Sérgio M., et al.
  Udgivet: (2019)
• Development of the first in vivo GPR17 ligand through an iterative drug discovery pipeline: A novel disease-modifying strategy for multiple sclerosis
  af: Parravicini, Chiara, et al.
  Udgivet: (2020)
• Computational analysis of ligand–receptor interactions in wild-type and mutant erythropoietin complexes
  af: Pekas, Nicholas J, et al.
  Udgivet: (2018)