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Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica
BACKGROUND: Aquaporin-4-immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune disease of the central nervous system in which AQP4-IgG binding to AQP4 on astrocytes results in complement-dependent astrocyte injury and secondary inflammati...
Gardado en:
| Publicado en: | J Neuroinflammation |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6198534/ https://ncbi.nlm.nih.gov/pubmed/30348195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1333-z |
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