Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica

BACKGROUND: Aquaporin-4-immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (herein called NMO) is an autoimmune disease of the central nervous system in which AQP4-IgG binding to AQP4 on astrocytes results in complement-dependent astrocyte injury and secondary inflammati...

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Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Duan, Tianjiao, Smith, Alex J., Verkman, Alan S.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198534/
https://ncbi.nlm.nih.gov/pubmed/30348195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1333-z
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