Noninvasive, Targeted Creation of Neuromyelitis Optica Pathology in AQP4-IgG Seropositive Rats by Pulsed Focused Ultrasound

Neuromyelitis optica spectrum disorders (herein called NMO) is an autoimmune disease of the CNS characterized by astrocyte injury, inflammation, and demyelination. In seropositive NMO, immunoglobulin G autoantibodies against aquaporin-4 (AQP4-IgG) cause primary astrocyte injury. A passive transfer m...

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Vydáno v:J Neuropathol Exp Neurol
Hlavní autoři: Yao, Xiaoming, Adams, Matthew S, Jones, Peter D, Diederich, Chris J, Verkman, Alan S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657442/
https://ncbi.nlm.nih.gov/pubmed/30500945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nly107
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