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Paternal germ line aging: DNA methylation age prediction from human sperm

BACKGROUND: The relationship between aging and epigenetic profiles has been highlighted in many recent studies. Models using somatic cell methylomes to predict age have been successfully constructed. However, gamete aging is quite distinct and as such age prediction using sperm methylomes is ineffec...

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Dades bibliogràfiques
Publicat a:BMC Genomics
Autors principals: Jenkins, Timothy G., Aston, Kenneth I., Cairns, Bradley, Smith, Andrew, Carrell, Douglas T.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198359/
https://ncbi.nlm.nih.gov/pubmed/30348084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5153-4
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