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Paternal germ line aging: DNA methylation age prediction from human sperm

BACKGROUND: The relationship between aging and epigenetic profiles has been highlighted in many recent studies. Models using somatic cell methylomes to predict age have been successfully constructed. However, gamete aging is quite distinct and as such age prediction using sperm methylomes is ineffec...

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Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Jenkins, Timothy G., Aston, Kenneth I., Cairns, Bradley, Smith, Andrew, Carrell, Douglas T.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198359/
https://ncbi.nlm.nih.gov/pubmed/30348084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-018-5153-4
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